The project SURE (Smart Launchers – Autonomous MVM and Monitoring Systems for Safe and Adaptable GNC System) focused on the development of smart launcher enabling technologies that pave the way for improved launcher robustness, reliability, safety and commercial application. This paper presents three innovative solutions derived in the project, in the areas of Guidance, Robust Control, and Safety, describing the principles of each one and highlighting the results achieved in high-fidelity validation, with a higher focus on the guidance topic. The real-time optimized guidance allows a launcher to autonomously update its trajectory, based on a tailored firstorder solver xPIPG, shown to be computationally more efficient than the standard ECOS. A robust control architecture with a wind disturbance observer and a load relief controller is shown to successfully minimize the load and the drift rate error, allowing for wider launch windows, with a solution that relies only on an engineering design that does not require any additional sensor or other hardware. A robust safety control methodology is also presented, employing Control Barrier Functions, ensuring that the vehicle remains within drift bounds and attitude errors. The proposed technologies are validated in high-fidelity Model-in-the-Loop (MIL) and also Software-inthe-Loop (SIL), achieving a high degree of representativity and suitability for future adoption in real applications. Additional developments, such as estimation of flexible modes, are also proposed.